DNBSEQ-T20×2 is a high-throughput sequencer that can support the simultaneous operation of six flow cells, enabling the completion of up to 50,000 whole genome sequencing cases per year. The cost of whole genome sequencing for an individual has been reduced to less than $100, setting a new record in global sequencing instrument throughput and single-person sequencing cost. Designed by Xiao Yu, Shiyou Wei, Kaijin Li, Feng Chen, and Dong Wei.