It is every medical design professional’s desire to improve the delivery of service within healthcare environments. Critical to achieving this goal is a thorough investigation of the hospital 'system.’ Systems design, design thinking and strategy along with educating oneself in advanced medical technology and materials will contribute to the improvement of these desired outcomes. This includes the understanding of the many user interactions with medical equipment during a typical use lifecycle and the options of sterilization procedures available for medical tool reprocessing. Considering that 1.7 million patients are infected each year during hospitalizations, there is a clear need to rethink hospital design and the equipment that runs through it. Pepe Velasquez's presentation will introduce the concept of the ‘burden of responsible knowledge’ which will compel design, and research and development professionals to acknowledge that they must educate themselves in vastly changing technologies whilst conceptualizing new medical tools and surgical techniques.